Unsubstituted Phenols
Medchemexpress LLC Ko 143 | 461054-93-3 | MFCD19053160 | 100.0% | 469.6 g/mol | C26H35N3O5 | 1 ML
Potent, selective ABCG2 (BCRP) inhibitor used to probe transporter function and multidrug resistance. Shows over 200-fold selectivity versus P-gp and MRP-1; supplied as a 10 mM solution in 1 mL for laboratory use.
- Potent and selective ABCG2 (BCRP) inhibitor for transporter studies.
- Displays greater than 200-fold selectivity over P-gp and MRP-1.
- Supplied as a 10 mM solution in 1 mL for convenient dosing.
- Molecular weight 469.6 g/mol and formula C26H35N3O5.
- CAS number 461054-93-3 for unambiguous identification.
eMolecules Medchem Express / Tilfrinib / 5mg / 482203923 / HY-110244 / / 1600515-49-8 / MFCD30011871 / 275.311 / C17H13N3O
Medchem Express / Tilfrinib / 5mg / 482203923 / HY-110244 / / 1600515-49-8 / MFCD30011871 / 275.311 / C17H13N3O
Medchemexpress LLC HY-18719C 5mg Medchemexpress, Endoxifen (E-isomer hydrochloride) CAS:1197194-61-8 Purity:>98%
Medchemexpress, HY-18719C 5mg Endoxifen (E-isomer hydrochloride) CAS:1197194-61-8 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC Ko 143 461054-93-3 10mg
Ko 143 (CAS 461054-93-3) is a selective inhibitor of the breast cancer resistance protein (BCRP/ABCG2) an ATP-binding cassette transporter implicated in multidrug resistance in cancer cells By targeting BCRP Ko 143 effectively blocks BCRP-mediated drug efflux as demonstrated by an EC90 of 26 nM in cell-based assays This compound exhibits over 200-fold selectivity for BCRP compared to P-glycoprotein and MRP1 In vitro Ko 143 reverses BCRP-mediated resistance to chemotherapeutics such as topotecan and mitoxantrone enhancing their potency up to tenfold in relevant cancer cell lines Ko 143 has been used in murine models to increase systemic exposure of BCRP substrates supporting its utility in studying drug resistance mechanisms and improving chemotherapeutic efficacy in preclinical research
Medchemexpress LLC Tyrphostin AG1433 | 168835-90-3 | 99.1% | 10MG
Tyrphostin AG1433 | 168835-90-3 | 99.1% | 10MG
Medchemexpress LLC HY-W041019 10mg Medchemexpress, 5-Hydroxytryptophol CAS:154-02-9 Purity:>98%
Medchemexpress, HY-W041019 10mg 5-Hydroxytryptophol CAS:154-02-9 5-Hydroxytryptophol is a mammalian serotonin metabolite, acting as a marker of acute alcohol consumption. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 4-Morpholin-4-yl-phenol | 6291-23-2 | 5G | Purity: 96%
Combi-Blocks | 4-Morpholin-4-yl-phenol | 5G | 6291-23-2 | MFCD00066933
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eMolecules Medchem Express / Isosakuranetin / 5mg / 446275689 / HY-N2131 / / 480-43-3 / [null] / 286.283 / C16H14O5
Medchem Express / Isosakuranetin / 5mg / 446275689 / HY-N2131 / / 480-43-3 / [null] / 286.283 / C16H14O5